Products
Captarose HR Resin (HIC)
Product Introduction
Captarose HR Hydrophobic Interaction Chromatography (HIC) Resin utilizes highly rigid agarose as the matrix with an average particle size of 40 μm. Functional groups are covalently immobilized onto agarose microspheres through stable chemical bonds. The charge-free ligands enable true hydrophobic interaction chromatography without ionic interference.
The matrix of Captarose HR is chemically modified and engineered from Singarose HP, exhibiting enhanced mechanical properties. It delivers high dynamic binding capacity and resolution under elevated flow rates, coupled with low backpressure, broad applicability, and superior kinetic performance. This makes it a preferred resin for large-scale separation and purification of biomolecules, particularly suitable for intermediate and polishing steps in purification processes.
Product Highlights
High Rigidity
Uniform Particle Size
High Resolution
Excellent Stability
Superior Reproducibility
Scalable
High Pressure Resistance, Low Back Pressure
Strong Hydrophilicity, Minimal Non-specific Adsorption
High Versatility, Broad Application Range
Technical Parameters
Product Name Phenyl Captarose HR Phenyl Captarose HR (LS) Butyl Captarose HR Octyl Captarose HR
Matrix Highly Rigid Agarose
Average Particle Size 40 µm
Ligand Phenyl Butyl Octyl
Ligand Density 10 µmol/mL resin 9 µmol/mL resin 50 µmol/mL resin 5 µmol/mL resin
Recommended Flow Rate <300 cm/h
Recommended Pressure <0.5 MPa (5 bar)
pH Stability 3-13 (Long-term*); 2-14 (Short-term*)
Chemical Stability Stable in common aqueous buffers including: 1 mM HCl, 1 M NaOH, 30% Isopropanol, 6 M Guanidine Hydrochloride, 8 M Urea, etc.
Operating Temperature 4-40℃
Storage Conditions 20% Ethanol; 4-30℃

Note *: Long-term refers to pH range where the resin maintains stability without compromising performance. Short-term refers to pH range for regeneration, in-place cleaning, and sterilization.

Ordering Information
Product Name Catalog No. Specification
Phenyl Captarose HR HC4030301 25 mL
HC4030302 100 mL
HC4030304 1 L
HC4030305 5 L
Phenyl Captarose HR (LS) HC4030601 25 mL
HC4030602 100 mL
HC4030604 1 L
HC4030605 5 L
Butyl Captarose HR HC4010201 25 mL
HC4010202 100 mL
HC4010204 1 L
HC4010205 5 L
Octyl Captarose HR HC4020201 25 mL
HC4020202 100 mL
HC4020204 1 L
HC4020205 5 L
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