Products
Captarose HF Resin (HIC)
Product Introduction
Captarose HF Hydrophobic Interaction Chromatography (HIC) Resin utilizes highly rigid agarose as the matrix with an average particle size of 75 μm. Functional groups are covalently immobilized onto agarose microspheres through stable chemical bonds. The charge-free ligands enable true hydrophobic interaction chromatography without ionic interference.
The matrix of Captarose HF is chemically modified and engineered from Singarose FF, exhibiting enhanced mechanical properties. It delivers high dynamic binding capacity under high flow rates, enabling rapid processing of large sample volumes. With characteristics including fast flow rates, low backpressure, broad applicability, and superior kinetic performance, this resin is a preferred choice for large-scale separation and purification of biomolecules, particularly suitable for initial capture and intermediate purification steps in purification processes.
Product Highlights
High Flow Rate
Low Back Pressure
High Pressure Resistance
Uniform Particle Size
Excellent Stability
Superior Reproducibility
Scalable
Strong Hydrophilicity, Minimal Non-specific Adsorption
High Versatility, Broad Application Range
Technical Parameters
Product Name Phenyl Captarose HF (HS) Phenyl Captarose HF (LS) Butyl Captarose HF Octyl Captarose HF
Matrix Highly Rigid Agarose
Average Particle Size 75 µm
Ligand Phenyl Butyl Octyl
Ligand Density 27 µmol/mL resin 22 µmol/mL resin 53 µmol/mL resin 5 µmol/mL resin
Recommended Flow Rate <600 cm/h
Recommended Pressure <0.5 MPa (5 bar)
pH Stability 3-13 (Long-term*); 2-14 (Short-term*)
Chemical Stability Stable in common aqueous buffers including: 1 mM HCl, 1 M NaOH, 30% Isopropanol, 6 M Guanidine Hydrochloride, 8 M Urea, etc.
Operating Temperature 4-40℃
Storage Conditions 20% Ethanol; 4-30℃

Note *: Long-term refers to pH range where the resin maintains stability without compromising performance. Short-term refers to pH range for regeneration, in-place cleaning, and sterilization.

Ordering Information
Product Name Catalog No. Specification
Phenyl Captarose HF (HS) HC4030401 25 mL
HC4030402 100 mL
HC4030404 1 L
HC4030405 5 L
Phenyl Captarose HF (LS) HC4030501 25 mL
HC4030502 100 mL
HC4030504 1 L
HC4030505 5 L
Butyl Captarose HF HC4010301 25 mL
HC4010302 100 mL
HC4010304 1 L
HC4010305 5 L
Octyl Captarose HF HC4020301 25 mL
HC4020302 100 mL
HC4020304 1 L
HC4020305 5 L
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